Wednesday, February 11, 2015
Sorin Group, a global medical device company and a leader in the treatment of cardiovascular diseases, announced today the first successful implants of the EquiliaTM system in the Vanguard (Vagal Nerve Stimulation Safeguarding Heart Failure Patients) clinical study. The system is intended to treat heart failure by stimulating the vagus nerve. Heart failure has been shown to be associated with an imbalance in the autonomic nervous system that controls cardiac activity. This imbalance, a reduction in parasympathetic activity and an increase in sympathetic activity, overstresses the heart and contributes to the worsening of heart failure1
By stimulating the vagus nerve, the Equilia system is expected to normalize the autonomic imbalance. The Equilia system consists of a small device implanted under the skin in the patient’s chest that delivers electrical pulses via the EquiCurl TM lead placed around the vagus nerve in the neck area.
“Neurostimulation is expected to prolong heart failure patients’ survival, improve their quality of life and reduce the number of hospital readmissions. I believe the Equilia system has the potential to bring significant benefits to heart failure patients,” said Professor Albert Hagège, Head of the Cardiology Department at the Hôpital Européen Georges Pompidou (HEGP), Paris, France and principal investigator in the Vanguard study.
The implant procedures were coordinated by Dr. Eloi Marijon, electrophysiologist at HEGP. Patients are also enrolled in the study at the Université Catholique de Louvain (UCL) Hospital in Brussels, Belgium by Dr. Jean-Benoît Le Polain de Waroux, electrophysiologist.
“Our New Ventures organization is actively working on several vagus nerve stimulation projects to treat heart failure disease. Equilia is New Ventures’ first innovation to enter clinical trials. Vagus nerve stimulation has the potential to expand the clinical indications for device-based therapies for heart failure and we look forward to bringing this exciting new therapy to the market”, said André-Michel Ballester, Chief Executive Officer, Sorin Group.
Source:http://www.sorin.com
