Research Insights

This section focusses on the cutting-edge research and findings in the various disciplines of healthcare around the world.

Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: A population-based cohort study

Some earlier studies have found indications of significant changes in cardiometabolic risk factors in children born after assisted reproductive technology ART Most of these studies are based on small cohorts with high risk of selection bias In this study we compared the risk of cardiovascular disease obesity and type diabetes

Death of an offspring and parental risk of ischemic heart diseases: A population-based cohort study

The death of a child is an extreme life event with potentially longterm health consequences Knowledge about its association with ischemic heart diseases IHDs and acute myocardial infarction AMI however is very limited We investigated whether the death of an offspring

Infectious complications and graft outcome following treatment of acute antibody-mediated rejection after kidney transplantation: A nationwide cohort study

Acute antibodymediated rejection AMR remains a challenge after kidney transplantation KT As there is no clearcut treatment recommendation accurate information on current therapeutic strategies in reallife practice is needed KT recipients from the multicenter Swiss Transplant Cohort Study treated for acute AMR during

Impact of chronic kidney disease on the short- and long-term outcomes of laparoscopic gastrectomy for gastric cancer patients

This study was undertaken to investigate the impact of coexisting chronic kidney disease CKD on short and longterm outcomes of laparoscopic gastrectomy in patients with gastric cancer GC In East Asia laparoscopic gastrectomy for gastric cancer GC is as safe and curative as open gastrectomy and has become the standard procedure for early

Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis

Coronavirus Disease COVID which was first identified in Wuhan Hubei Province China in December has already swept across the world The World Health Organization WHO has officially declared the outbreak as a pandemic and a public health emergency

Real-time gastrointestinal infection surveillance through a cloud-based network of clinical laboratories

Acute gastrointestinal infection AGI represents a significant public health concern To control and treat AGI it is critical to quickly and accurately identify its causes The use of novel multiplex molecular assays for pathogen detection and identification provides a unique opportunity to improve pathogen detection and better understand risk factors

Clinical and CT characteristics of Xpert MTB/RIF-negative pulmonary tuberculosis

To determine the diagnostic accuracy of the Xpert MTBRIF assay in patients with smearnegative pulmonary tuberculosis TB and to assess clinical and CT characteristics of Xpertnegative pulmonary TB

Evaluation of potential COVID-19 recurrence in patients with late repeat positive SARS-CoV-2 testing

SARSCoV reinfection and reactivation has mostly been described in case reports We therefore investigated the epidemiology of recurrent COVID SARSCoV The risk of recurrent COVID resulting from SARSCoV reinfection or reactivation is currently unknown Persistent detection of viral RNA for at least days after patients initial positive assay is well de...

The association of estimated cardiorespiratory fitness with COVID-19 incidence and mortality: A cohort study

It has been suggested that cardiorespiratory fitness CRF may be used to identify those at greatest risk for severe COVID illness However no study to date has examined the association between CRF and COVID The objectives of this study were to determine whether CRF is independently associated with testing positive

Effects of incomplete inter-hospital network data on the assessment of transmission dynamics of hospital-acquired infections

In the year there were different statutory insurance companies in Germany with heterogeneous regional coverage Obtaining data from all insurance companies is challenging so that it is likely that projects will have to rely on data not covering the whole population Consequently the study of epidemic spread in hospital referral networks

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