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This section focusses on the cutting-edge research and findings in the various disciplines of healthcare around the world.
Abstract Background This study aimed to evaluate whether prompting general practitioners GPs to routinely assess and manage anxiety and depression in patients consulting with osteoarthritis OA improves pain outcomes Methods and findings We conducted a cluster randomised controlled trial involving English general practices In intervention pract...
Abstract Background Immune infiltration of breast tumours is associated with clinical outcome However past work has not accounted for the diversity of functionally distinct cell types that make up the immune response The aim of this study was to determine whether differences in the cellular composition of the i
Abstract Zika virus has only recently gained attention due to recent large outbreaks worldwide An easy to use nucleic acid amplification test could play an important role in the early detection of the infection and patient management Here we report a rapid and robust isothermal nucleic acid amplification assay for the detection of Zika virus The m...
New and reemerging pathogens with epidemic potential have threatened global health security for the past century As with the recent Ebola Virus Disease EVD epidemic the Zika Virus ZIKV outbreak has yet again surprised and overwhelmed the international health community with an unexpected event for which it might have been better prepared ZIKV was f...
Summary Diagnostic yield of endomyocardial biopsy is low particularly in disease that affects the myocardium in a nonuniform distribution The authors hypothesized that realtime MRI guidance could improve the yield through targeted biopsy of focal myocardial pathology They tested this hypothesis in an animal model of focal myocardial pathology usin...
Abstract Objective To assess DWI and ADC value in characterization of orbital masses differentiation of benign inflammatory and malignant orbital masses Patients methods Crosssectional study included pati
Abstract The authors present a case of fat embolism syndrome after traumatic longbone fracture in a patient with rapid neurologic deterioration and multiple cerebral embolic events Diagnostic workup revealed the neuroradiologic findings classically described with cerebral fat emboli The authors present hallmark ultrasound imaging of echogenic mate...
Abstract Introduction Our goal was to develop cut points for amyloid positron emission tomography PET tau PET flourodeoxyglucose FDG PET and MRI cortical thickness Methods We examined five methods for determin
Abstract Registration of vascular structures is crucial for preoperative planning intraoperative navigation and followup assessment Typical applications include but are not limited to Transcatheter Aortic Valve Implantation and monitoring of tumor vasculature or aneurysm growth In order to achieve the aforementioned goals a large number of various...
Abstract Arthroereisis is a rare and disputed procedure where an implant screw is inserted into the sinus tarsi to treat flatfoot deformity Weightbearing radiographs are the most essential examinations to assess the correct localization and related measurements Hardware loosening is the most common complication seen as localized lucency and as dis...
