Research Insights

This section focusses on the cutting-edge research and findings in the various disciplines of healthcare around the world.

Infectious complications and graft outcome following treatment of acute antibody-mediated rejection after kidney transplantation: A nationwide cohort study

Acute antibodymediated rejection AMR remains a challenge after kidney transplantation KT As there is no clearcut treatment recommendation accurate information on current therapeutic strategies in reallife practice is needed KT recipients from the multicenter Swiss Transplant Cohort Study treated for acute

Low serum albumin and the risk of hospitalization in COVID-19 infection: A retrospective case-control study

Coronavirus disease COVID was first reported almost a year ago Many studies have been done and much has been learned about the disease The patients who have worse outcomes generally have overwhelming inflammatory response as evidenced

Derivation and External Validation of a Risk Score for Predicting HIV-Associated Tuberculosis to Support Case Finding and Preventive Therapy Scale-Up: A Cohort Study

Among people living with HIV PLHIV more flexible and sensitive tuberculosis TB screening tools capable of detecting both symptomatic and subclinical active TB are needed to reduce morbidity and mortality from undiagnosed TB facilitate scaleup of tuberculosis preventive therapy TPT while reducing inappropriate prescription of TPT

The Blood Metabolome of Incident Kidney Cancer: A Case–Control Study Nested within the Metkid Consortium

Excess bodyweight and related metabolic perturbations have been implicated in kidney cancer aetiology but the specific molecular mechanisms underlying these relationships are poorly understood In this study we sought to identify circulating metabolites that predispose kidney cancer and to evaluate the extent to which they are influenced

Cardiovascular disease, obesity, and type 2 diabetes in children born after assisted reproductive technology: A population-based cohort study

Some earlier studies have found indications of significant changes in cardiometabolic risk factors in children born after assisted reproductive technology ART Most of these studies are based on small cohorts with high risk of selection bias In this study we compared the risk of cardiovascular disease obesity and type diabetes

Death of an offspring and parental risk of ischemic heart diseases: A population-based cohort study

The death of a child is an extreme life event with potentially longterm health consequences Knowledge about its association with ischemic heart diseases IHDs and acute myocardial infarction AMI however is very limited We investigated whether the death of an offspring

Infectious complications and graft outcome following treatment of acute antibody-mediated rejection after kidney transplantation: A nationwide cohort study

Acute antibodymediated rejection AMR remains a challenge after kidney transplantation KT As there is no clearcut treatment recommendation accurate information on current therapeutic strategies in reallife practice is needed KT recipients from the multicenter Swiss Transplant Cohort Study treated for acute AMR during

Impact of chronic kidney disease on the short- and long-term outcomes of laparoscopic gastrectomy for gastric cancer patients

This study was undertaken to investigate the impact of coexisting chronic kidney disease CKD on short and longterm outcomes of laparoscopic gastrectomy in patients with gastric cancer GC In East Asia laparoscopic gastrectomy for gastric cancer GC is as safe and curative as open gastrectomy and has become the standard procedure for early

Clinical determinants of the severity of COVID-19: A systematic review and meta-analysis

Coronavirus Disease COVID which was first identified in Wuhan Hubei Province China in December has already swept across the world The World Health Organization WHO has officially declared the outbreak as a pandemic and a public health emergency

Real-time gastrointestinal infection surveillance through a cloud-based network of clinical laboratories

Acute gastrointestinal infection AGI represents a significant public health concern To control and treat AGI it is critical to quickly and accurately identify its causes The use of novel multiplex molecular assays for pathogen detection and identification provides a unique opportunity to improve pathogen detection and better understand risk factors

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