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China Medical University Hospital's AISIA Revolutionizes Acute Ischemic Stroke Diagnosis in 90 Seconds, Assisting Swift Medical Decisions

Wednesday, April 03, 2024

The Neurology Department of China Medical University Hospital (CMUH) in Taiwan, collaborating with the AI Center at CMUH, has developed the AISIA (Artificial Intelligence for Stroke Image Analysis) platform. This groundbreaking platform includes two key components: the "NCCT-based Ischemic Stroke Detection System (AISIA-NCCT)" and the "Brain CT Perfusion Analysis System (AISIA-CTP)," both of which were created by the AI Center at CMUH. These systems analyze NCCT and CTP images to swiftly detect acute ischemic stroke and identify crucial factors like the ischemic core and penumbra. By assisting physicians in making critical decisions regarding acute ischemic stroke management, AISIA aims to significantly improve patient outcomes.

AISIA-NCCT employs deep learning techniques to train AI models using data from nearly four hundred patients. This enables the system to detect the presence of acute ischemic stroke in just 90 seconds, surpassing traditional manual interpretation with impressive accuracy rates. Specifically, AISIA-NCCT achieves a remarkable 92.5% accuracy, along with 100% sensitivity and 89.7% specificity in detecting brain ischemia exceeding 70mL. Such advancements empower healthcare professionals with enhanced decision-making capabilities when diagnosing and treating stroke cases.

Published in "Biomedical Signal Processing and Control, Volume 93, 2024," this study underscores the critical role of CT imaging in diagnosing stroke, a condition with profound implications for patients' physical well-being and mortality.

While brain CTP offers valuable insights into ischemic stroke diagnosis and damage assessment, its reliance on contrast medium injection poses risks, including contrast-induced nephropathy, nausea, vomiting, and aspiration pneumonia. For patients unable to receive contrast media due to contraindications, AISIA-NCCT provides a viable alternative for evaluating CTP.

Stroke, occurring predominantly in ischemic form (80%) in Taiwan, arises from cerebrovascular occlusion, leading to compromised blood and oxygen supply and consequent brain cell damage. Swift identification of acute ischemic stroke and delineation of salvageable areas are pivotal for effective treatment and recovery.

Survivors of stroke often undergo prolonged rehabilitation to restore their functional independence. However, many patients experience lasting disabilities, imposing significant burdens on both society and families.