Publisher: Academic Press
Year of Publication: 2020
Author(s) : Grazyna Soderbom Russell Esterline Jan Oscarsson Mark Mattson
Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative disorders, particularly Alzheimer’s and Parkinson’s, as well as increasing evidence for the overlap between drivers of metabolic syndrome and neurodegenerative disorders that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Cells Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Disorders, Role of Senescence in Aging and Aging-Related Disease with Emphasis on and Implications for Neurodegenerative Disorders, Evidence for Pathophysiological Commonalities between Metabolic and Neurodegenerative Disorders, Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Disorders, and much more.