Role Of Diffusion Weighted Imaging In Characterization Of Pancreatic Pathology

Authors: Eman Salah Mohammed Abdallah, Mohamed Ibrahim Mahmoud Ali, Maryse Yousef Awadallah, Hamed Samir Hamed El Ghawabi

Abstract:

Purpose

The purpose of the study was to show the value of combination of conventional MRI with DWI to raise the sensitivity and specificity considering the differentiation between pancreatic benign and malignant lesions.

Patients and Methods

Study included 30 patients performed in the radiology department, Cairo University, as well as in a private center: 21 males and 9 females. Age of patients ranged between 27 and 76 years.

The study was performed between August 2012 and April 2014. Patients were subjected to proper history taking, conventional MRI and DWI.

Result

In our study using combined qualitative analysis of diffusion weighted imaging and quantitative analysis of ADC values we found that results of diffusion weighted MRI are approaching that of contrast enhanced MRI not only in detecting pancreatic tumors but also in detection of tumor necrosis and liver metastasis which are essential information to reflect disease prognosis and treatment strategies.

Keywords

Pancreas; ADC; MRI; Pancreatic neoplasms; Diffusion

Citation: Eman Salah Mohammed Abdallah, Mohamed Ibrahim Mahmoud Ali, Maryse Yousef Awadallah, Hamed Samir Hamed El Ghawabi Role Of Diffusion Weighted Imaging In Characterization Of Pancreatic Pathology doi:10.1016/j.ejrnm.2016.05.019

Received: 3 April 2016, Accepted: 30 May 2016, Available online: 16 June 2016

Copyright: © 2016 The Egyptian Society of Radiology and Nuclear Medicine. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Conclusion

Combined qualitative and quantitative analysis of DWIs and ADC values respectively made the results of DW MRI approach that of contrast enhanced MRI not only in detection of pancreatic neoplasms but also in detection of tumor necrosis and liver metastasis. Using DWI in conjunction with conventional imaging as a useful modality aids in assessment of pancreatic neoplasms. In cases with contraindication to contrast administration DWI can be used as an alternative technique to contrast-enhanced imaging.

Key points

Assess sensitivity and specificity of DWI in differentiating benign from malignant lesions.

Conflict of interest

The authors declare that they have no conflict of interest.

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